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What's the Deal: Rock and Republic, MOCFA's 50 Under $50 and so many more...

Sometimes, you just gotta deal...

Rock and Republic: Score 50 to 80 percent off retail on this label’s premium denim, outwear and accessories for men, women and children during a weekend sample sale at Fort Mason.

Museum of Craft and Folk Art: For the holidays, the museum store showcases 50 items under $50 by local artists with the 50 Under $50 collection, comprised of items exclusive to the shop.

Pacific Shaving: Put your camera phone to good use with this promotion from the local shaving company. Buy any two products at a local retailer that carriers the brand (Whole Foods is among them), take a picture of the receipt making sure the store name and date of purchase are clearly visible and email the image to customerservice (at) pacificshaving (dot) com. Within 72 hours, the company promises to send you your choice of ½ oz. shaving oil or a Nick Stick free.

Jack’s: Bring eight or more non-perishable food items to either store by Dec. 14, and the destination for hip menswear will reward you with 20 percent off anything in the store.

Custom Industries: Need to stock up on hip t-shirts and hoodies? A clearance sale from this local label means men’s and women’s cotton graphic hoodies and tees are 50 percent off, with prices ranging from $13 for women’s shirts and $15 for men’s to $40 for men’s sweatshirts.

Shotwell: Fancy a little help with your holiday shopping? You’ll get a free “personal shopper” at this Union Square destination for independent designers, as well as discounts on much of the merchandise in the store.

Goorin Bros.: Take 20 percent off all web orders through Dec. 14 with the discount code holiday09.

Serial Cultura: In Oakland, an open studio holiday sale on Saturday from this local designer promises clothing and scarves at 50 percent off, with prices for scarves starting at $30.

Harputs Union: Save $100 purchases of $300 or more through the end of 2009 at this Geary destination for inventive apparel from designers such as Pleasure Principle, Martha Davis, Tellason, Comme des Garcons and Jan Warnock.

Sample Angel: You’ll save an additional 15 percent off purchases this weekend at this Presidio Heights go-to for discounted designer apparel.

Shana Astrachan: This local jewelry designer is offering 15 percent off purchases made through her etsy shop during an online sale that runs through Dec. 18.

Sean: This men’s store with locations in Cow Hollow and Hayes Valley is offering $25 off purchases of $100 or more through the end of the year.

Isso: You’ll find a storewide 30 percent off sale at these Noe Valley and Mission boutiques this weekend.

The Marine Store: You’ll save 10 percent on orders under $100 with the discount code TAM and 15 percent on purchases over $100 with the discount code STINSON during this online boutique’s Friends and Family Sale, running now through Dec. 22.

Oxenrose: Along with 20 percent off purchases of three or more products from lines such as Kerastase, Magic Move, Bumble and bumble and DS Labs and 50 percent off Kerastase In-Salon Ritual treatments, this Hayes Valley salon is offering a chance to give and receive. Donate a new and unwrapped toy for a boy or girl ages 1 though 12 to the salon’s toy drive (part of the annual San Francisco Firefighters Toy Program) anytime through Tuesday, and you’ll receive a rewards card for 10 percent off retail purchases.

Looking for more? There are major deals to be had at the bevy of neighborhood shopping events, arts and crafts fairs and sample sales taking place starting this weekend and running through the holidays. Check out 12 Non-Mall Holiday Shopping Events for all the details on events such as tonight’s Mission Block Party and this weekend’s Haute Holidays event at the Bentley Reserve.